Expertise area
Our expertise in industrial biotechnology revolves around three key areas:
Fermentation, Enzymatic Catalysis, and Separation and Purification.
We specialize in both biological catalysts (microorganisms and enzymes)
and the processes for their application and purification.
Fermentation
IN LIQUID OR SOLID MEDIA
Our Offer
From the development of innovative processes to the optimization of existing ones, we contribute to numerous projects utilizing bacteria, yeasts, fungi, and microalgae.
Objectives
These projects have various goals, such as the production of biomass, value-added molecules (peptides, proteins, enzymes, antibiotics, chemical synthons, bioethanol…), or the transformation of raw materials.
Achievements
We can develop or adapt cultivation conditions in bioreactors (batch, fed-batch, continuous), conduct microbiological and physico-chemical monitoring of fermentations in liquid or solid media, and standardize pre-culture steps to facilitate scaling up.
Examples of Fermentation Projects
- Development of an indigenous ferment for AOP Rocamadour cheese.
- Establishing a cultivation method for Klamath microalgae (scientific name: Aphanizomenon flos aquae) in collaboration with Kyanos Nutrition.
- Cultures of bacterial and yeast strains for enzyme production in food applications.
- Optimization of enzymatic hydrolysis and alcoholic fermentation conditions for cellulose pulp derived from straw pretreated using the Organosolv process.
- Development of natural and sustainable antifungal solutions for viticulture, arboriculture, and market gardening.
- Algal process development for biomolecule production.
enzymatiC
CatalysIS
Our Offer
Experts in the development and optimization of enzymatic catalysis processes, we contribute to many projects involving enzymes. Our expertise also includes enzyme stabilization and immobilization.
Objectives
Enzymatic catalysis enables bioconversion, synthesis, hydrolysis, or functionalization for the production of active ingredients for food, pharmaceuticals, cosmetics, and more.
Achievements
We specialize in chaining downstream process (DSP) unit operations, including: Cell disruption, Centrifugation, Membrane processes (microfiltration, ultrafiltration, nanofiltration, reverse osmosis), Electrodialysis, Chromatography, Lyophilization, Drying
Examples of Enzyme Engineering Projects
- Industrial-scale development for enzyme production, plastic hydrolysis, and monomer purification for plastic recycling, in collaboration with Carbios, TBI, and TWB.
- Enzymatic hydrolysis of waste for biopolymer flocculants, such as alginate, using a microbial consortium.
- Development of a medical device with immobilized enzymes for autologous blood transformation.
- Studying the degradation of antinutritional factors in legumes for the Pasta Seniors project in partnership with Nutrinat.
- Immobilization of enzymes (hydrolases, isomerases, transferases) for pharmaceutical (racemic resolution) and food applications.
- Implementation of industrial enzymes in continuous reactors.
- Screening fungi strains for the production of specific enzymes.
- Optimization, purification, immobilization, and continuous bioconversion implementation of enzymes.
SEparation
& purification
Our Offer
Experts in separation and purification techniques, we develop or optimize processes to meet your specific needs.
Objectives
Separation and purification processes are designed to isolate and stabilize active ingredients produced through fermentation or enzymatic pathways.
Achievements
We are skilled in chaining downstream process (DSP) unit operations, such as: Cell extraction, Centrifugation, Membrane processes (microfiltration, ultrafiltration, nanofiltration, reverse osmosis), Electrodialysis, Chromatography, Lyophilization, Drying
Examples of Purification and Stabilization Projects
- Development of a purification process for an adhesive resin produced by fermentation as part of the Bioimpulse collaborative project.
- Designing a separation technique to eliminate contaminant microorganisms from a microalgae culture.
- Testing and developing biosensors for detecting aquatic biotoxins.
- Optimizing production, stabilization, and concentration conditions for a natural biocide obtained from plant fermentation.
- Developing a process for extracting and purifying sugars from downgraded apples.
A proven track record with
